Why Do We Get Allergies? Allergies are your body’s reaction to things it considers “foreign.” They are also a sign that your immune system is working overtime, or is already under stress. When your body comes in contact with foreign material (allergens such as pollen, pet dander, etc.), your plasma cells release an antibody called immunoglobulin E (IgE). These antibodies attach to the surface of your mast cells. Your surface tissues (like your skin and mucous membranes in the sinus cavity/nose, etc.) have a large number of mast cells. These help mediate inflammatory responses by releasing several substances, one of which is histamine. When your body comes in contact with that same aller
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